I've always used saddlebags by tying them to the saddlebag loops on my bike. I recently decided to try visiting the office, now that I'm fully vaccinated, and stuck my Macbook Pro 16 into my Carradice Camper Longflap, and then rode it. The Camper swallows everything I can throw at it, and the Macbook was no exception, but then what I discovered that the saddlebag then hits my thigh as I ride. (I'd previously never had the problem on tour, because I'd never stuck such a large flat, rigid object in the saddlebag before) And before you say it, yes, saddlepack systems like the Revelate Terrapin are all the rage for cycle touring, but none of those will ever fit a laptop of any size, let alone the giant-ass inconveniently designed Macbook Pro 16.
OK, let's try the SQR system. It retails for about $50 after shipping from England, and boasts the additional advantage of doubling as a quick release with a handle. It was worth a try. The device is a little tricky --- you have to remove the saddle and slide it on along with the spring and then position it facing directly backwards. But I installed it without a problem, and discovered that I had enough seatpost both before and after the offset part of my Thomson offset seatpost, so those of you with offset seatposts don't have to worry --- even if it doesn't fit below the kink, it will fit above the kink!
In the lowest position, the bag clears the rear wheel, and doesn't touch the thigh. But it turns out that you can lift it higher, to the offset section of the Thomson seat post with no problems. The problem is that unless you stuff the bag full of stuff (like on tour), it sags, so I had to do the cross-strap trick. But that made the radar unusable.
So I stole my wife's beautiful Sackville Bag, and lo and behold, no sag, no problem. It truly is a much better designed bag than the Carradice (as it ought to be, for $100 more!). It even clears the fender!
But as you can see, the Macbook sticks out like a tongue. And to be honest, the Sackville was so small that it didn't need the SQR block, which weighs 149g for the block, 248g for the frame, and 7g for the strap handle, adding nearly a pound to the bike. So I guess I'll steal the Sackville bag for summer riding, and go back to my Timbuk2 for rainy rides where I need to carry the Macbook, which are rare now that I'm in a drought. Or maybe I'll find a way to downgrade to a smaller laptop that doesn't stick out.